Brain Development

I. Growth & development of new cells
  1. proliferation: the productions of neurons during early development

  2. migration: some neurons must move to their eventual location

  3. differentiation: the distinctive parts (e.g., axons) of the neuron develop

  4. myelination: myelin develops on some axons

  5. synaptogenesis:  formation of synapses

II. Neural survival
  1. many neurons develop (more than you need) only necessary ones survive

  2. finding appropriate targets is important for neuron survival
    A. target cells release neurotrophins: chemicals that promote neuron survival & growth
      a. e.g., nerve growth factor promotes survival of presynaptic cells
    B. apoptosis: dying of cells without targets  

III. How do axons find their targets after injury
  1. some cells release chemicals that attract certain axons & repel others

  2. many synapses may develop but only the most appropriate ones survive

  3. Schwann cells form a tube for axons to grow in the PNS

IV. Experience is important
  1. enriched versus impoverished environment in rats

  2. more educated humans have more widely branched dendrites

V. Is brain size correlated with IQ scores in humans?
 

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